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Natural killer cell licensing in mice with inducible expression of MHC class I
Mouse natural killer (NK) cells acquire effector function by an education process termed “licensing” mediated by inhibitory Ly49 receptors which recognize self-MHC class I. Ly49 receptors can bind to MHC class I on targets (in trans) and also to MHC class I on the NK-cell surface (in cis). Which of...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3831452/ https://ncbi.nlm.nih.gov/pubmed/24145414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318255110 |
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