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Ligand-specific conformational change of the G-protein–coupled receptor ALX/FPR2 determines proresolving functional responses
Formyl-peptide receptor type 2 (FPR2), also called ALX (the lipoxin A4 receptor), conveys the proresolving properties of lipoxin A(4) and annexin A1 (AnxA1) and the proinflammatory signals elicited by serum amyloid protein A and cathelicidins, among others. We tested here the hypothesis that ALX mig...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3831442/ https://ncbi.nlm.nih.gov/pubmed/24108355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308253110 |
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