The Melanocortin Agonist AP214 Exerts Anti-Inflammatory and Proresolving Properties

Synthetic and natural melanocortin (MC) peptides afford inhibitory properties in inflammation and tissue injury, but characterization of receptor involvement is still elusive. We used the agonist AP214 to test MC-dependent anti-inflammatory effects. In zymosan peritonitis, treatment of mice with AP2...

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Bibliographische Detailangaben
Hauptverfasser: Montero-Melendez, Trinidad, Patel, Hetal B., Seed, Michael, Nielsen, Søren, Jonassen, Thomas E.N., Perretti, Mauro
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2011
Schlagworte:
Regular Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123798/
https://ncbi.nlm.nih.gov/pubmed/21703408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.03.042
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