The Melanocortin Agonist AP214 Exerts Anti-Inflammatory and Proresolving Properties

Synthetic and natural melanocortin (MC) peptides afford inhibitory properties in inflammation and tissue injury, but characterization of receptor involvement is still elusive. We used the agonist AP214 to test MC-dependent anti-inflammatory effects. In zymosan peritonitis, treatment of mice with AP2...

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Autori principali: Montero-Melendez, Trinidad, Patel, Hetal B., Seed, Michael, Nielsen, Søren, Jonassen, Thomas E.N., Perretti, Mauro
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2011
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Regular Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123798/
https://ncbi.nlm.nih.gov/pubmed/21703408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.03.042
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