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Correction of mutations within the cystic fibrosis transmembrane conductance regulator by site-directed RNA editing
Adenosine deaminases that act on RNA are a conserved family of enzymes that catalyze a natural process of site-directed mutagenesis. Biochemically, they convert adenosine to inosine, a nucleotide that is read as guanosine during translation; thus when editing occurs in mRNAs, codons can be recoded a...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3831439/ https://ncbi.nlm.nih.gov/pubmed/24108353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306243110 |
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