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Natural IgG antibodies provide innate protection against ficolin-opsonized bacteria

For nearly five decades since its discovery, the role of natural IgG, which pre-exists in neonates and uninfected individuals, has remained unclear due to the general perception that natural antibodies lack affinity for pathogens. Here, we show for the first time that natural IgG recognizes a spectr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Panda, Saswati, Zhang, Jing, Tan, Nguan Soon, Ho, Bow, Ding, Jeak Ling
Format: Artigo
Sprache:Inglês
Veröffentlicht: European Molecular Biology Organization 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831310/
https://ncbi.nlm.nih.gov/pubmed/24002211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.199
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