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Natural IgG antibodies provide innate protection against ficolin-opsonized bacteria

For nearly five decades since its discovery, the role of natural IgG, which pre-exists in neonates and uninfected individuals, has remained unclear due to the general perception that natural antibodies lack affinity for pathogens. Here, we show for the first time that natural IgG recognizes a spectr...

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Hlavní autoři: Panda, Saswati, Zhang, Jing, Tan, Nguan Soon, Ho, Bow, Ding, Jeak Ling
Médium: Artigo
Jazyk:Inglês
Vydáno: European Molecular Biology Organization 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831310/
https://ncbi.nlm.nih.gov/pubmed/24002211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.199
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