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Natural IgG antibodies provide innate protection against ficolin-opsonized bacteria

For nearly five decades since its discovery, the role of natural IgG, which pre-exists in neonates and uninfected individuals, has remained unclear due to the general perception that natural antibodies lack affinity for pathogens. Here, we show for the first time that natural IgG recognizes a spectr...

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Detalhes bibliográficos
Main Authors: Panda, Saswati, Zhang, Jing, Tan, Nguan Soon, Ho, Bow, Ding, Jeak Ling
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831310/
https://ncbi.nlm.nih.gov/pubmed/24002211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.199
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