Flavonoid Regulation of HCN2 Channels

The hyperpolarization-activated cyclic nucleotide-modulated (HCN) channels are pacemaker channels whose currents contribute to rhythmic activity in the heart and brain. HCN channels open in response to hyperpolarizing voltages, and the binding of cAMP to their cyclic nucleotide-binding domain (CNBD)...

Full description

Saved in:
Bibliographic Details
Main Authors: Carlson, Anne E., Rosenbaum, Joel C., Brelidze, Tinatin I., Klevit, Rachel E., Zagotta, William N.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Molecular Biophysics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831264/
https://ncbi.nlm.nih.gov/pubmed/24085296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.501759
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items