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A 680 kb duplication at the FTO locus in a kindred with obesity and a distinct body fat distribution
Common intronic SNPs in the human fat mass and obesity associated (FTO) gene are strongly associated with body mass index (BMI). In mouse models, inactivation of the Fto gene results in a lean phenotype, whereas overexpression of Fto leads to increased food intake and obesity. The latter finding sug...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3831078/ https://ncbi.nlm.nih.gov/pubmed/23591406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2013.63 |
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