Functional Analysis of the TRIB1 Associated Locus Linked to Plasma Triglycerides and Coronary Artery Disease

BACKGROUND: The TRIB1 locus has been linked to hepatic triglyceride metabolism in mice and to plasma triglycerides and coronary artery disease in humans. The lipid‐associated single nucleotide polymorphisms (SNPs), identified by genome‐wide association studies, are located ≈30 kb downstream from TRI...

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Опубликовано в: :J Am Heart Assoc
Главные авторы: Douvris, Adrianna, Soubeyrand, Sébastien, Naing, Thet, Martinuk, Amy, Nikpay, Majid, Williams, Andrew, Buick, Julie, Yauk, Carole, McPherson, Ruth
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Publishing Ltd 2014
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309087/
https://ncbi.nlm.nih.gov/pubmed/24895164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.000884
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