Vaccinia Virus Induces Programmed Necrosis in Ovarian Cancer Cells

The mechanisms by which oncolytic vaccinia virus induces tumor cell death are poorly understood. We have evaluated cell death pathways following infection of ovarian cancer cells with both wild-type and thymidine kinase-deleted (dTK) Lister strain vaccinia. We show that death does not rely upon clas...

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Detalhes bibliográficos
Main Authors: Whilding, Lynsey M, Archibald, Kyra M, Kulbe, Hagen, Balkwill, Frances R, Öberg, Daniel, McNeish, Iain A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831043/
https://ncbi.nlm.nih.gov/pubmed/23985697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.195
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