Humanized Lewis-Y specific antibody based delivery of STAT3 siRNA

The clinical application of siRNA is limited largely by the lack of efficient, cell-specific delivery systems. Antibodies are attractive delivery vehicles for targeted therapy due to their high specificity. In this study we describe the use of a humanized monoclonal antibody (mAb), hu3S193, against...

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Bibliographic Details
Main Authors: Ma, Yuelong, Kowolik, Claudia M., Swiderski, Piotr M., Kortylewski, Marcin, Yu, Hua, Horne, David A., Jove, Richard, Caballero, Otavia L., Simpson, Andrew J.G., Lee, Fook-Thean, Pillay, Vinochani, Scott, Andrew M.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831028/
https://ncbi.nlm.nih.gov/pubmed/21766840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200176v
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