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Regulation of T cell receptor signaling by the actin cytoskeleton and poroelastic cytoplasm

The actin cytoskeleton plays essential roles in modulating T-cell activation. Most models of T-cell receptor (TCR) triggering, signalosome assembl, y and immune synapse formation invoke actin-dependent mechanisms. As T cells are constitutively motile cells, TCR triggering and signaling occur against...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Beemiller, Peter, Krummel, Matthew F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831008/
https://ncbi.nlm.nih.gov/pubmed/24117819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12120
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