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Real-time analysis of T cell receptors in naive cells in vitro and in vivo reveals flexibility in synapse and signaling dynamics

The real-time dynamics of the T cell receptor (TCR) reflect antigen detection and T cell signaling, providing valuable insight into the evolving events of the immune response. Despite considerable advances in studying TCR dynamics in simplified systems in vitro, live imaging of subcellular signaling...

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Bibliografiske detaljer
Main Authors: Friedman, Rachel S., Beemiller, Peter, Sorensen, Caitlin M., Jacobelli, Jordan, Krummel, Matthew F.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989766/
https://ncbi.nlm.nih.gov/pubmed/21041455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091201
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