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T Cell Signal Regulation by the Actin Cytoskeleton

T cells form an immunological synapse (IS) that sustains and regulates signals for cell stimulation. Enriched in the IS is the Src family kinase Lck. Conversely, the membrane phosphatase CD45, which activates Src family kinases, is excluded, and this is necessary to avoid quenching of T cell recepto...

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Autori principali: Chichili, Gurunadh R., Westmuckett, Andrew D., Rodgers, William
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863167/
https://ncbi.nlm.nih.gov/pubmed/20194498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.097311
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