Compartmentalization of Phosphatidylinositol 4,5-Bisphosphate Signaling Evidenced Using Targeted Phosphatases

Phosphatidylinositol 4,5-bisphosphate (PIP(2)) is a prevalent phosphoinositide in cell membranes, with important functions in cell signaling and activation. A large fraction of PIP(2) associates with the detergent-resistant membrane “raft” fraction, but the functional significance of this associatio...

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Bibliographische Detailangaben
Hauptverfasser: Johnson, Corey M., Chichili, Gurunadh R., Rodgers, William
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Membrane Transport, Structure, Function, and Biogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573053/
https://ncbi.nlm.nih.gov/pubmed/18723502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805921200
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