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T Cell Signal Regulation by the Actin Cytoskeleton
T cells form an immunological synapse (IS) that sustains and regulates signals for cell stimulation. Enriched in the IS is the Src family kinase Lck. Conversely, the membrane phosphatase CD45, which activates Src family kinases, is excluded, and this is necessary to avoid quenching of T cell recepto...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2863167/ https://ncbi.nlm.nih.gov/pubmed/20194498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.097311 |
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