טוען...
Mutagenic Spectra Arising from Replication Bypass of the 2,6-diamino-4-hydroxy-N(5)-methyl Formamidopyrimidine Adduct in Primate Cells
DNA exposures to electrophilic methylating agents that are commonly used during chemotherapeutic treatments cause diverse chemical modifications of nucleobases, with reaction at N7-dG being the most abundant. Although this base modification frequently results in destabilization of the glycosyl bond...
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| Main Authors: | , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3830661/ https://ncbi.nlm.nih.gov/pubmed/23763662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx4001495 |
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