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Tyrosine Phosphorylation of Mig6 Reduces its Inhibition of the Epidermal Growth Factor Receptor

Under physiological conditions, epidermal growth factor receptor (EGFR) tyrosine kinase activity is tightly controlled through the coordinated action of both positive and negative regulators. Aberrant EGFR activation occurs frequently in many cancer types and the endogenous EGFR feedback inhibitor,...

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Détails bibliographiques
Auteurs principaux: Wang, Zhihong, Raines, Lily, Hooy, Richard M., Roberson, Heather, Leahy, Daniel J., Cole, Philip A.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3830645/
https://ncbi.nlm.nih.gov/pubmed/24004111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb4005707
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