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Protein tyrosine phosphatase 1B interacts with and is tyrosine phosphorylated by the epidermal growth factor receptor.

We used a substrate-trapping technique to search for substrates of protein tyrosine phosphatase (PTP) 1B. A catalytically inactive form of this enzyme forms a stable, phosphotyrosine-dependent complex with epidermal growth factor receptor (EGFR) both in vitro and in cells. PTP1B also interacts with...

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Detalles Bibliográficos
Main Authors: Liu, F, Chernoff, J
Formato: Artigo
Idioma:Inglês
Publicado: 1997
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1218773/
https://ncbi.nlm.nih.gov/pubmed/9355745
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