Identification of Driver Genes in Hepatocellular Carcinoma by Exome Sequencing

Genetic alterations in specific driver genes lead to disruption of cellular pathways and are critical events in the instigation and progression of hepatocellular carcinoma. As a prerequisite for individualized cancer treatment, we sought to characterize the landscape of recurrent somatic mutations i...

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Detalhes bibliográficos
Main Authors: Cleary, Sean P., Jeck, William R., Zhao, Xiaobei, Chen, Kui, Selitsky, Sara R., Savich, Gleb L., Tan, Ting-Xu, Wu, Michael C., Getz, Gad, Lawrence, Michael S., Parker, Joel S., Li, Jinyu, Powers, Scott, Kim, Hyeja, Fischer, Sandra, Guindi, Maha, Ghanekar, Anand, Chiang, Derek Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3830584/
https://ncbi.nlm.nih.gov/pubmed/23728943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26540
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