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Validation of miRNA-mRNA interactions by electrophoretic mobility shift assays

BACKGROUND: MicroRNAs are small non-coding RNAs involved in gene expression regulation by targeting specific regions in the 3′-UTR of the mRNA of their target genes. This binding leads to a decrease in the protein levels of such genes either by mRNA degradation or mRNA destabilization and translatio...

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Autori principali: Solé, Anna, Mencia, Núria, Villalobos, Xenia, Noé, Véronique, Ciudad, Carlos J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3830445/
https://ncbi.nlm.nih.gov/pubmed/24215842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-6-454
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