Progastrin Stimulates Colonic Cell Proliferation via CCK2R- and β-Arrestin–Dependent Suppression of BMP2

BACKGROUND & AIMS: Progastrin stimulates colonic mucosal proliferation and carcinogenesis through the cholecystokinin 2 receptor (CCK2R)—partly by increasing numbers of colonic progenitor cells. However, little is known about the mechanisms by which progastrin stimulates colonic cell proliferati...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jin, Guangchun, Westphalen, C. Benedikt, Hayakawa, Yoku, Worthley, Daniel L., Asfaha, Samuel, Yang, Xiangdong, Chen, Xiaowei, Si, Yiling, Wang, Hongshan, Tailor, Yagnesh, Friedman, Richard A., Wang, Timothy C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829714/
https://ncbi.nlm.nih.gov/pubmed/23891976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.07.034
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