p,p′-DDE activates CatSper and compromises human sperm function at environmentally relevant concentrations

STUDY QUESTION: Is the environmental endocrine disruptor p,p′-dichlorodiphenyldichloroethylene (p,p′-DDE) able to induce non-genomic changes in human sperm and consequently affect functional sperm parameters? SUMMARY ANSWER: p,p′-DDE promoted Ca(2+) flux into human sperm by activating CatSper channe...

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Hlavní autoři: Tavares, Renata S., Mansell, Steven, Barratt, Christopher L.R., Wilson, Stuart M., Publicover, Stephen J., Ramalho-Santos, João
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829580/
https://ncbi.nlm.nih.gov/pubmed/24067601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/det372
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