Genome-Wide RNAi High-Throughput Screen Identifies Proteins Necessary for the AHR-Dependent Induction of CYP1A1 by 2,3,7,8-Tetrachlorodibenzo-p-dioxin

The aryl hydrocarbon receptor (AHR) has a plethora of physiological roles, and upon dysregulation, carcinogenesis can occur. One target gene of AHR encodes the xenobiotic and drug-metabolizing enzyme CYP1A1, which is inducible by the environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCD...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Solaimani, Parrisa, Damoiseaux, Robert, Hankinson, Oliver
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829574/
https://ncbi.nlm.nih.gov/pubmed/23997114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kft191
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