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2,3,7,8- Te trachlorodibenzo-p-dioxin treatment alters eicosanoid levels in several organs of the mouse in an aryl hydrocarbon receptor-dependent fashion

2,3,7,8- Te trachlorodibenzo- p-dioxin (TCDD) adversely affects many mammalian organs and tissues. These effects are mediated by the aryl hydrocarbon receptor (AHR). CYP1A1, CYP1A2 and CYP1B1 are upregulated by the liganded AHR. These (and other) cytochromes P450 can metabolize arachidonic acid into...

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Hlavní autoři: Bui, Peter, Solaimani, Parrisa, Wu, Xiaomeng, Hankinson, Oliver
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288243/
https://ncbi.nlm.nih.gov/pubmed/22230337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2011.12.009
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