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MUC1-C Oncoprotein Activates ERK→C/EBPβ Signaling and Induction of Aldehyde Dehydrogenase 1A1 in Breast Cancer Cells

Aldehyde dehydrogenase 1A1 (ALDH1A1) activity is used as a marker of breast cancer stem cells; however, little is known about the regulation of ALDH1A1 expression. Mucin 1 (MUC1) is a heterodimeric protein that is aberrantly overexpressed in most human breast cancers. In studies of breast cancer cel...

詳細記述

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書誌詳細
主要な著者: Alam, Maroof, Ahmad, Rehan, Rajabi, Hasan, Kharbanda, Akriti, Kufe, Donald
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829404/
https://ncbi.nlm.nih.gov/pubmed/24043631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.477158
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