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MUC1-C Oncoprotein Activates ERK→C/EBPβ Signaling and Induction of Aldehyde Dehydrogenase 1A1 in Breast Cancer Cells

Aldehyde dehydrogenase 1A1 (ALDH1A1) activity is used as a marker of breast cancer stem cells; however, little is known about the regulation of ALDH1A1 expression. Mucin 1 (MUC1) is a heterodimeric protein that is aberrantly overexpressed in most human breast cancers. In studies of breast cancer cel...

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Autori principali: Alam, Maroof, Ahmad, Rehan, Rajabi, Hasan, Kharbanda, Akriti, Kufe, Donald
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829404/
https://ncbi.nlm.nih.gov/pubmed/24043631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.477158
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