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Conserved Aromatic Residue Confers Cation Selectivity in Claudin-2 and Claudin-10b
In tight junctions, both claudin-2 and claudin-10b form paracellular cation-selective pores by the interaction of the first ECL 1 with permeating ions. We hypothesized that a highly conserved aromatic residue near the pore selectivity filter of claudins contributes to cation selectivity by cation-π...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3829363/ https://ncbi.nlm.nih.gov/pubmed/23760508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.484238 |
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