Amino-terminal Domain Tetramer Organization and Structural Effects of Zinc Binding in the N-Methyl-d-aspartate (NMDA) Receptor

N-Methyl-d-aspartate (NMDA) receptors mediate excitatory neurotransmission in the mammalian central nervous system. An important feature of these receptors is their capacity for allosteric regulation by small molecules, such as zinc, which bind to their amino-terminal domain (ATD). Zinc inhibition t...

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Bibliografske podrobnosti
Main Authors: Sirrieh, Rita E., MacLean, David M., Jayaraman, Vasanthi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Neurobiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829342/
https://ncbi.nlm.nih.gov/pubmed/23792960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.482356
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