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Amino-terminal Domain Tetramer Organization and Structural Effects of Zinc Binding in the N-Methyl-d-aspartate (NMDA) Receptor

N-Methyl-d-aspartate (NMDA) receptors mediate excitatory neurotransmission in the mammalian central nervous system. An important feature of these receptors is their capacity for allosteric regulation by small molecules, such as zinc, which bind to their amino-terminal domain (ATD). Zinc inhibition t...

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Bibliografische gegevens
Hoofdauteurs: Sirrieh, Rita E., MacLean, David M., Jayaraman, Vasanthi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829342/
https://ncbi.nlm.nih.gov/pubmed/23792960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.482356
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