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Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

Resident mouse peritoneal macrophages were shown to take up and degrade acetylated (125)I-labeled low density lipoprotein ((125)I-acetyl-LDL) in vitro at rates that were 20-fold greater than those for the uptake and degradation of (125)I-LDL. The uptake of (125)I-acetyl-LDL and its subsequent degrad...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Goldstein, Joseph L., Ho, Y. K., Basu, Sandip K., Brown, Michael S.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1979
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC382933/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/218198/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.1.333
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