Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

Resident mouse peritoneal macrophages were shown to take up and degrade acetylated (125)I-labeled low density lipoprotein ((125)I-acetyl-LDL) in vitro at rates that were 20-fold greater than those for the uptake and degradation of (125)I-LDL. The uptake of (125)I-acetyl-LDL and its subsequent degrad...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Goldstein, Joseph L., Ho, Y. K., Basu, Sandip K., Brown, Michael S.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1979
Assuntos:	Biological Sciences: Cell Biology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC382933/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/218198/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.1.333
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