Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

Resident mouse peritoneal macrophages were shown to take up and degrade acetylated (125)I-labeled low density lipoprotein ((125)I-acetyl-LDL) in vitro at rates that were 20-fold greater than those for the uptake and degradation of (125)I-LDL. The uptake of (125)I-acetyl-LDL and its subsequent degrad...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Goldstein, Joseph L., Ho, Y. K., Basu, Sandip K., Brown, Michael S.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1979
Schlagworte:	Biological Sciences: Cell Biology
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC382933/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/218198/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.1.333
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