Crucial Role for Phylogenetically Conserved Cytoplasmic Loop 3 in ABCC4 Protein Expression

The ABC transporter ABCC4 is recognized as an ATP-dependent exporter of endogenous substances as well as an increasing variety of anionic chemotherapeutics. A loss-of-function variant of zebrafish Abcc4 was identified with a single amino acid substitution in the cytoplasmic loop T804M. Because this...

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Hauptverfasser: Cheepala, Satish B., Bao, Ju, Nachagari, Deepa, Sun, Daxi, Wang, Yao, Zhong, Tao, Naren, Anjaparavanda P., Zheng, Jie, Schuetz, John D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829313/
https://ncbi.nlm.nih.gov/pubmed/23766510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.476218
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