The ABCC4 membrane transporter modulates platelet aggregation

Controlling the activation of platelets is a key strategy to mitigate cardiovascular disease. Previous studies have suggested that the ATP-binding cassette (ABC) transporter, ABCC4, functions in platelet-dense granules. Using plasma membrane biotinylation and super-resolution microscopy, we demonstr...

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Pubblicato in:Blood
Autori principali: Cheepala, Satish B., Pitre, Aaron, Fukuda, Yu, Takenaka, Kazumasa, Zhang, Yuanyuan, Wang, Yao, Frase, Sharon, Pestina, Tamara, Gartner, T. Kent, Jackson, Carl, Schuetz, John D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2015
Soggetti:
Platelets and Thrombopoiesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643005/
https://ncbi.nlm.nih.gov/pubmed/26405223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-08-595942
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