Loop Motions Important to Product Expulsion in the Thermobifida fusca Glycoside Hydrolase Family 6 Cellobiohydrolase from Structural and Computational Studies

Cellobiohydrolases (CBHs) are typically major components of natural enzyme cocktails for biomass degradation. Their active sites are enclosed in a tunnel, enabling processive hydrolysis of cellulose chains. Glycoside hydrolase Family 6 (GH6) CBHs act from nonreducing ends by an inverting mechanism a...

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Autores principales: Wu, Miao, Bu, Lintao, Vuong, Thu V., Wilson, David B., Crowley, Michael F., Sandgren, Mats, Ståhlberg, Jerry, Beckham, Gregg T., Hansson, Henrik
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Computational Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829159/
https://ncbi.nlm.nih.gov/pubmed/24085303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.502765
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