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The contact allergen nickel sensitizes primary human endothelial cells and keratinocytes to TRAIL-mediated apoptosis

Primary endothelial cells are fully resistant to TNF-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis. Here, we demonstrate that certain environmental conditions, such as exposure to the widespread allergen nickel, can dramatically increase the susceptibility of naturally resistant prima...

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Detalhes bibliográficos
Main Authors: Schmidt, Marc, Hupe, Mike, Endres, Nicole, Raghavan, Badrinarayanan, Kavuri, Shyam, Geserick, Peter, Goebeler, Matthias, Leverkus, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829037/
https://ncbi.nlm.nih.gov/pubmed/19538462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00823.x
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