TRAF2 inhibits TRAIL- and CD95L-induced apoptosis and necroptosis

The relevance of the adaptor protein TNF receptor-associated factor 2 (TRAF2) for signal transduction of the death receptor tumour necrosis factor receptor1 (TNFR1) is well-established. The role of TRAF2 for signalling by CD95 and the TNF-related apoptosis inducing ligand (TRAIL) DRs, however, is on...

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Publicat a:Cell Death Dis
Autors principals: Karl, I, Jossberger-Werner, M, Schmidt, N, Horn, S, Goebeler, M, Leverkus, M, Wajant, H, Giner, T
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649511/
https://ncbi.nlm.nih.gov/pubmed/25299769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.404
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