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Parameters of oligonucleotide-mediated gene modification in mouse ES cells
Gene targeting by single-stranded oligodeoxyribonucleotides (ssODNs) is emerging as a powerful tool for the introduction of subtle gene modifications in mouse embryonic stem (ES) cells and the generation of mutant mice. Here, we have studied the role of ssODN composition, transcription and replicati...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3829028/ https://ncbi.nlm.nih.gov/pubmed/19627401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00847.x |
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