Neurotrophic factors promote cholinergic differentiation in human embryonic stem cell-derived neurons

Cholinergic neurotransmission is essential for many important functions in the brain, including cognitive mechanisms. Here we demonstrate that human embryonic stem (hES) cells differentiate into a population of neuronal cells that express the cholinergic enzyme choline acetyltransferase and homeobox...

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Autors principals: Nilbratt, Mats, Porras, Omar, Marutle, Amelia, Hovatta, Outi, Nordberg, Agneta
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2010
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829014/
https://ncbi.nlm.nih.gov/pubmed/19799651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00916.x
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