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Modulation of human neural stem cell differentiation in Alzheimer (APP23) transgenic mice by phenserine

In a previous study, we found that human neural stem cells (HNSCs) exposed to high concentrations of secreted amyloid-precursor protein (sAPP) in vitro differentiated into mainly astrocytes, suggesting that pathological alterations in APP processing during neurodegenerative conditions such as Alzhei...

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Auteurs principaux: Marutle, Amelia, Ohmitsu, Masao, Nilbratt, Mats, Greig, Nigel H., Nordberg, Agneta, Sugaya, Kiminobu
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2007
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1941499/
https://ncbi.nlm.nih.gov/pubmed/17640880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705346104
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