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Neurotrophic and Neuroprotective Actions of (−)- and (+)-Phenserine, Candidate Drugs for Alzheimer’s Disease

Neuronal dysfunction and demise together with a reduction in neurogenesis are cardinal features of Alzheimer’s disease (AD) induced by a combination of oxidative stress, toxic amyloid-β peptide (Aβ) and a loss of trophic factor support. Amelioration of these was assessed with the Aβ lowering AD expe...

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Bibliografiska uppgifter
Huvudupphovsmän: Lilja, Anna M., Luo, Yu, Yu, Qian-sheng, Röjdner, Jennie, Li, Yazhou, Marini, Ann M., Marutle, Amelia, Nordberg, Agneta, Greig, Nigel H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3559887/
https://ncbi.nlm.nih.gov/pubmed/23382994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054887
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