β-Amyloid 1-42 Oligomers Impair Function of Human Embryonic Stem Cell-Derived Forebrain Cholinergic Neurons

Cognitive impairment in Alzheimer's disease (AD) patients is associated with a decline in the levels of growth factors, impairment of axonal transport and marked degeneration of basal forebrain cholinergic neurons (BFCNs). Neurogenesis persists in the adult human brain, and the stimulation of r...

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Detalhes bibliográficos
Main Authors: Wicklund, Linn, Leão, Richardson N., Strömberg, Anne-Marie, Mousavi, Malahat, Hovatta, Outi, Nordberg, Agneta, Marutle, Amelia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003688/
https://ncbi.nlm.nih.gov/pubmed/21179413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015600
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