β-Amyloid 1-42 Oligomers Impair Function of Human Embryonic Stem Cell-Derived Forebrain Cholinergic Neurons

Cognitive impairment in Alzheimer's disease (AD) patients is associated with a decline in the levels of growth factors, impairment of axonal transport and marked degeneration of basal forebrain cholinergic neurons (BFCNs). Neurogenesis persists in the adult human brain, and the stimulation of r...

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Autores principales: Wicklund, Linn, Leão, Richardson N., Strömberg, Anne-Marie, Mousavi, Malahat, Hovatta, Outi, Nordberg, Agneta, Marutle, Amelia
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003688/
https://ncbi.nlm.nih.gov/pubmed/21179413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015600
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