Deregulation of keratinocyte differentiation and activation: a hallmark of venous ulcers

Epidermal morphology of chronic wounds differs from that of normal epidermis. Biopsies of non-healing edges obtained from patients with venous ulcers show thick and hyperproliferative epidermis with mitosis present in suprabasal layers. This epidermis is also hyper-keratotic and parakeratotic. This...

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Bibliografiske detaljer
Main Authors: Stojadinovic, Olivera, Pastar, Irena, Vukelic, Sasa, Mahoney, Mỹ G, Brennan, Donna, Krzyzanowska, Agata, Golinko, Michael, Brem, Harold, Tomic-Canic, Marjana
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2008
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828883/
https://ncbi.nlm.nih.gov/pubmed/18373736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00321.x
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