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Death receptors as targets for anti-cancer therapy

Human tumour cells are characterized by their ability to avoid the normal regulatory mechanisms of cell growth, division and death. The classical chemotherapy aims to kill tumour cells by causing DNA damage-induced apoptosis. However, as many tumour cells posses mutations in intracellular apoptosis-...

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Detalles Bibliográficos
Main Authors: Papenfuss, Kerstin, Cordier, Stefanie M, Walczak, Henning
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828874/
https://ncbi.nlm.nih.gov/pubmed/19210756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00514.x
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