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Death receptors as targets in cancer
Anti-tumour therapies based on the use pro-apoptotic receptor agonists, including TNF-related apoptosis-inducing ligand (TRAIL) or monoclonal antibodies targeting TRAIL-R1 or TRAIL-R2, have been disappointing so far, despite clear evidence of clinical activity and lack of adverse events for the vast...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Blackwell Publishing Ltd
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3753832/ https://ncbi.nlm.nih.gov/pubmed/23638798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12238 |
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