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Targeting survival pathways in chronic myeloid leukaemia stem cells
Chronic myeloid leukaemia (CML) is a clonal myeloproliferative disorder characterized by the presence of a fusion oncogene BCR-ABL, which encodes a protein with constitutive TK activity. The implementation of tyrosine kinase inhibitors (TKIs) marked a major advance in CML therapy; however, there are...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3753830/ https://ncbi.nlm.nih.gov/pubmed/23517124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12183 |
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