Death receptors as targets for anti-cancer therapy

Human tumour cells are characterized by their ability to avoid the normal regulatory mechanisms of cell growth, division and death. The classical chemotherapy aims to kill tumour cells by causing DNA damage-induced apoptosis. However, as many tumour cells posses mutations in intracellular apoptosis-...

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Bibliografiske detaljer
Main Authors: Papenfuss, Kerstin, Cordier, Stefanie M, Walczak, Henning
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2008
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828874/
https://ncbi.nlm.nih.gov/pubmed/19210756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00514.x
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