Adenosine augments IL-10-induced STAT3 signaling in M2c macrophages

The alternatively activated macrophage phenotype induced by IL-10 is called M2c. Adenosine is an endogenous purine nucleoside that accumulates in the extracellular space in response to metabolic disturbances, hypoxia, inflammation, physical damage, or apoptosis. As adenosine is known to regulate cla...

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Bibliographic Details
Main Authors: Koscsó, Balázs, Csóka, Balázs, Kókai, Endre, Németh, Zoltán H., Pacher, Pál, Virág, László, Leibovich, S. Joseph, Haskó, György
Format: Artigo
Language:Inglês
Published: Society for Leukocyte Biology 2013
Subjects:
Inflammation, Extracellular Mediators, & Effector Molecules
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828607/
https://ncbi.nlm.nih.gov/pubmed/23922379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0113043
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